Connective Tissue - Safety Data

ABSOLUTE ETHANOL: is a flammable liquid and should never be handled close to heat or a naked flame. The vapour is heavier than air and can travel for a considerable distance along the ground to a source of ignition and flash back. Ethanol is regarded as one of the safest industrial solvents. Although it possesses narcotic properties, vapour concentrations sufficient to produce narcosis are rarely, if ever reached in a medical laboratory. Ethanol is rapidly oxidised, in the body, to carbon dioxide and water and does not produce permanent damage to the central nervous system.
EYES - Code 1; SKIN - Code 4; INHALED - Code 14; INGESTED - Code 18

ACETIC ACID: is a corrosive substance and will cause severe damage to exposed skin. Ingestion will cause dental erosion, bronchitis and respiratory difficulties. It is an eye and mucous membrane irritant.
EYES - Code 3; SKIN - Code 5; INHALED - Code 14; INGESTED - Code 20

ACID FUCHSIN: is a triaminotriarylmethane dye. It is a skin, eye and mucous membrane irritant and is toxic if ingested. It can cause conjunctivitis and prolonged skin contact may cause dermatitis. Ingestion may cause nausea, vomiting and diarrhoea.
EYES - Code 3; SKIN - Code 12; INHALED - Code 16; INGESTED - Code 24

ALUMINIUM POTASSIUM SULPHATE: is a skin and eye irritant and is mildly toxic when ingested. There is insufficient data on the effects of inhalation. Acute exposure to the eyes or skin may cause redness or pain. Ingestion may cause abdominal pain, vomiting and diarrhoea.
EYES - Code 2; SKIN - Code 5; INHALED - Code 14; INGESTED - Code 21

AMMONIA SOLUTION: is a severe irritant and is corrosive. Severe burns may be caused by skin or eye contact with the solution. Irritation of the respiratory tract can lead to convulsive coughing and permanent lung damage.
EYES - Code 3; SKIN - Code 5; INHALED - Code 16; INGESTED - Code 27

ANILINE BLUE: is a triaminotriarylmethane dye. It is a potential bladder carcinogen. It is very toxic and can be absorbed through the skin and respiratory tract. It can cause liver and kidney damage and anaemia.
EYES - Code 2; SKIN - Code 12; INHALED - Code 16; INGESTED - Code 24

AZURE A: is a thiazin dye. Little is known about the hazards associated with its use but other thiazin dyes are known to be highly toxic, mutagens and skin and eye irritants (methylene blue, thionin and toluidine blue). Handle with care. The dye should not be handled during pregnancy.
EYES - Code 3; SKIN - Code 13; INHALED - Code 16; INGESTED - Code 24

BIEBRICH SCARLET: is a disazo dye. Its effects on humans have not been quantified but other dyes in this group are known to be highly toxic.
EYES - Code 3; SKIN - Code 12; INHALED - Code 16; INGESTED - Code 24

BORAX: is an eye irritant and a toxic substance. It causes desquamation, vomiting and diarrhoea with depression of the circulatory system with resultant shock.
EYES - Code 2; SKIN - Code 5; INHALED - Code 14; INGESTED - Code 30

CELESTIN BLUE: is a quinone-imine dye. Its effects have not been quantified but other dyes in this group are potential carcinogens. Handle with care.
EYES - Code 2; SKIN - Code 12; INHALED - Code 16; INGESTED - Code 24

CHLORAL HYDRATE: is very toxic and an eye and skin irritant. Inhalation or ingestion may cause nausea, vomiting, coldness of limbs and unconsciousness.
EYES - Code 2; SKIN - Code 5; INHALED - Code 16; INGESTED - Code 24

CHROMOTROPE 2R: is a monoazo dye. The toxic effects upon humans have not been quantified but other dyes in this group are known to be carcinogenic and very toxic. Handle with care.
EYES - Code 3; SKIN - Code 12; INHALED - Code 15; INGESTED - Code 21

CITRIC ACID: is a skin, eye and respiratory tract irritant and a corrosive substance. It is a combustible solid and should never be handled close to heat or a naked flame.
EYES - Code 2; SKIN - Code 4; INHALED - Code 15; INGESTED - CODE 21

CRYSTAL PONCEAU 2R: is a monoazo dye. It is a known carcinogen and very toxic.
EYES - Code 3; SKIN - Code 13; INHALED - Code 16; INGESTED - Code 24

CRYSTAL VIOLET: is a triaminotriarylmethane dye which is a potential carcinogen, a mutagen and is highly toxic. It is an eye, skin and mucous membrane irritant and should not be handled during pregnancy.
EYES - Code 2; SKIN - Code 12; INHALED - Code 16; INGESTED - Code 24

DEXTRIN: is hygroscopic and prolonged skin contact may cause dermatitis and cracked skin. It is an eye irritant.
EYES - Code 1; SKIN - Code 5; INHALED - Code 14; INGESTED - Code 18

DISODIUM HYDROGEN ORTHOPHOSPHATE: is a toxic substance and can be absorbed into the body by inhalation or ingestion. It is an eye and skin irritant. Inhalation or ingestion may cause sore throat, coughing and abdominal pain. Eye and skin contact may cause redness and pain.
EYES - Code 2; SKIN - Code 5; INHALED - Code 14; INGESTED - Code 21

EOSIN Y: has been reported as being carcinogenic. This has not been confirmed but eosin Y is a bromofluorescein dye and other dyes in this group (phloxine and methyl eosin) are highly toxic. Eosin Y is a skin and eye irritant.
EYES - Code 2; SKIN - Code 5; INHALED - Code 16; INGESTED - Code 28

FAST RED SALT B: is a diazonium salt and is a potential carcinogen and an irritant to eyes and the respiratory tract. It should be handled with great care.
EYES - Code 3; SKIN - Code 5; INHALED - Code 15; INGESTED - Code 20

FERRIC CHLORIDE: is moderately toxic and a skin, eye and respiratory tract irritant. It is a strong irritant and moderately corrosive. Skin contact should be avoided.
EYES - Code 3; SKIN - Code 9; INHALED - Code 16; INGESTED - Code 27

FERRIC SULPHATE: is an eye and skin irritant and is mildly toxic. Ingestion will cause severe abdominal pain.
EYES - Code 2; SKIN - Code 5; INHALED - Code 15; INGESTED - Code 20

FORMALDEHYDE: is a moderately flammable liquid when exposed to heat or a naked flame. It is an animal carcinogen, a strong eye, skin and mucous membrane irritant and it is a skin sensitiser. Death has been reported in workers exposed to high levels of formalin vapour.
EYES - Code 3; SKIN - Code 12; INHALED - Code 16; INGESTED - Code 24

GIEMSA: is composed of a mixture of dyes which normally includes azure A, azure B and methylene blue. All are quinone-imine dyes in the thiazin sub group and all are very toxic and irritate eyes and skin. The powder is flammable and should never be handled close to heat or a naked flame.
EYES - Code 2; SKIN - Code 5; INHALED - Code 16; INGESTED - Code 28

GLYCEROL: is an eye irritant, otherwise it is regarded as being safe. It is hygroscopic and prolonged skin contact can cause dermatitis in sensitive individuals.
EYES - Code 2; SKIN - Code 11; INHALED - Code 14; INGESTED - Code 19.

GOLD CHLORIDE: is an eye irritant and may irritate the skin of sensitive individuals. It is regarded as being of low toxicity.
EYES - Code 2; SKIN - Code 4; INHALED - Code 14; INGESTED - Code 19

HAEMATIN: The effects of this compound are unknown. Handle with care.
EYES - Code 2; SKIN - Code 12; INHALED - Code 14; INGESTED - Code 20

HAEMATOXYLIN: is a natural dye. It is a flammable powder and should not be handled close to heat or a naked flame. It is a mild irritant to eyes, skin and mucous membranes. Its toxicity has not been quantified. Handle with care.
EYES - Code 2; SKIN - Code 11; INHALED - Code 14; INGESTED - Code 19

HYDROCHLORIC ACID: is a strong irritant and corrosive and must be handled with great care. It will cause severe burns to exposed skin and eyes. The vapour is also a strong irritant and corrosive. Always use a fume hood when handling this acid. ALWAYS add acid to water and NEVER water to acid as heat is generated which can cause a violent reaction.
EYES - Code 3; SKIN - Code 9; INHALED - Code 14; INGESTED - Code 22

IODINE: is a toxic and corrosive solid which attacks the central nervous system and the gastro intestinal tract. It can cause kidney damage and can be absorbed through the skin in doses large enough to cause toxicity. Inhalation can cause erosion of the respiratory tract. Over exposure to iodine vapour can be fatal. This is a very dangerous substance and should be handled with extreme care.
EYES - Code 3; SKIN - Code 5; INHALED - Code 16; INGESTED - Code 31

IRON ALUM: is an eye and skin irritant and is mildly toxic. Ingestion will cause severe abdominal pain.
EYES - Code 2: SKIN - Code 5; INHALED - Code 15; INGESTED - Code 20

LIGHT GREEN: is a diaminotriarylmethane dye. It is a combustible powder and should never be handled close to heat or naked flame. It is a known carcinogen and should be handled with extreme care. Avoid skin contact and inhaling the powder. It is an eye and respiratory tract irritant.
EYES - Code 3; SKIN - Code 12; INHALED - Code 15; INGESTED - Code 20

LITHIUM CARBONATE: is a potential carcinogen, an irritant and a corrosive substance. It will cause burns to exposed skin and eyes.
EYES - Code 3; SKIN - Code 12; INHALED - Code 15; INGESTED - Code 26

MARTIUS YELLOW: is a nitro dye. It is very toxic and can be absorbed through the skin in doses large enough to cause toxicity. It is an eye, skin and respiratory tract irritant.
EYES - Code 2; SKIN - Code 13; INHALED - Code 16; INGESTED - Code 24

MERCURIC CHLORIDE: is toxic and corrosive. It may be absorbed into the body by inhalation, ingestion or through the skin. Toxicity is accumulative and can cause blurred vision, sore throat, metallic taste, coughing, shortness of breath and laboured breathing. It is toxic to the kidneys and the central nervous system and can be fatal.
EYES - Code 3; SKIN - Code 7; INHALED - Code 15; INGESTED - Code 27

METHENAMINE (hexamethylenetetramine): is a flammable solid and should not be handled nor stored close to heat or naked flame. It is an eye, skin and mucous membrane irritant. Formaldehyde is liberated after acid hydrolysis therefore if ingested the formaldehyde produced will cause severe gastrointestinal upsets. Cystitis, haematuria and renal lesions may be produced.
EYES - Code 2; SKIN - Code 5; INHALED - Code 14; INGESTED - Code 21

METHYL BLUE: is a triaminotriphenylmethane dye. It is a combustible powder and should never be handled close to heat or naked flame. Its toxicity has not been quantified but other dyes in this group are carcinogenic. Handle with care.
EYES - Code 2; SKIN - Code 12; INHALED - Code 16; INGESTED - Code 24

MOUNTING MEDIUM: usually xylene or toluene based and the effects are as for xylene.
EYES - Code 2; SKIN - Code 12; INHALED - Code 15; INGESTED - Code 27

N-DIMETHYL FORMAMIDE: is an embryotoxin and a potential carcinogen. It must never be handled during pregnancy. It is an eye, skin and respiratory tract irritant. Ingestion may cause irreversible liver damage.
EYES - Code 3; SKIN - Code 6; INHALED - Code 16; INGESTED - Code 29

NAPHTHOL-AS-D CHLOROACETATE: is a potential carcinogen and should not be handled during pregnancy. It is an eye, skin and respiratory tract irritant and is moderately toxic.
EYES - Code 3; SKIN - Code 9; INHALED - Code 14; INGESTED - Code 20

NEUTRAL RED: is an azin dye, it is a toxic and a combustible powder and the powder should never be handled close to heat or a naked flame. It is an eye and skin irritant and may cause dermatitis.
EYES - Code 3; SKIN - Code 6; INHALED - Code 16; INGESTED - Code 21

NEW FUCHSIN: is an aminotriarylmethane dye. It is a combustible powder and should never be handled close to heat or a naked flame. It is an eye irritant. Its toxicity has not been quantified but other dyes in this group are known to be very toxic and potential carcinogens. Handle with care.
EYES - Code 3; SKIN - Code 12; INHALED - Code 16; INGESTED - Code 21

ORCEIN: is a quinone-imine dye in the oxazin sub group. Little is known about the hazards associated with its use however other dyes in this sub group are known to be hazardous to health. Handle with care.
EYES - Code 2; SKIN - Code 5; INHALED - Code 16; INGESTED - Code 28

OXALIC ACID: is a severe eye and skin irritant and can cause permanent eye damage. If ingested it can cause severe internal pain and collapse.
EYES - Code 2; SKIN - Code 5; INHALED - Code 15; INGESTED - Code 21

PARAROSANILIN: is a triaminotriphenylmethane dye. It is a potential carcinogen and as such should be handled with care. Its toxicity has not been quantified.
EYES - Code 2; SKIN - Code 11; INHALED - Code 14; INGESTED - Code 19

PERIODIC ACID: in contact with a combustible material may cause fire. It is a severe respiratory tract irritant and is a corrosive substance, causing severe burns to exposed skin and eyes.
EYES - Code 2; SKIN - Code 9; INHALED - Code 16; INGESTED - Code 22

PHOSPHOMOLYBDIC ACID: is a skin and eye irritant. It is toxic if inhaled or ingested. Molybdenum compounds are rapidly excreted from the body so that small doses rarely cause more than discomfort.
EYES - Code 2; SKIN - Code 12; INHALED - Code 16; INGESTED - Code 21

PHOSPHOTUNGSTIC ACID: is an eye irritant and is mildly corrosive. It is harmful to inhale the powder.
EYES - Code 2; SKIN - Code 12; INHALED - Code 15; INGESTED - Code 21

PICRIC ACID: is a strong oxidising agent and reacts violently with combustible material and reducing agents. It is toxic and can be absorbed into the body by inhalation of the vapour or ingestion of the liquid. It is an eyes, skin and respiratory tract irritant, a neurotoxin and can cause convulsions. The powder is explosive when dry and should therefore always be stored under water in a container with a cork stopper.
EYES - Code 2; SKIN - Code 6; INHALED - Code 16; INGESTED - Code 21

PONCEAU 2R: is a monoazo dye. It is a known carcinogen and very toxic.
EYES - Code 3; SKIN - Code 13; INHALED - Code 16; INGESTED - Code 24

PONCEAU S: is a combustible powder and should never be handled close to heat or a naked flame. It is a disazo dye, many of which are carcinogenic. It is an eye and respiratory tract irritant. It should be handled with great care and always beneath a fume hood.
EYES - Code 3; SKIN - Code 12; INHALED - Code 16; INGESTED - Code 24

POTASSIUM DIHYDROGEN ORTHOPHOSPHATE: is an eye and respiratory tract irritant. There is only slight toxicity if ingested, however, if large amounts are ingested it may cause metabolic disturbances.
EYES - Code 2; SKIN - Code 11; INHALED - Code 14; INGESTED - Code 20

POTASSIUM IODIDE: is highly corrosive and toxic. It is a severe eye and respiratory tract irritant and will cause burns to the skin. If ingested it will cause severe abdominal pain. Inhalation will do irreversible damage to the lungs.
EYES - Code 2; SKIN - Code 6; INHALED - Code 16; INGESTED - Code 31

POTASSIUM PERMANGANATE: is an oxidising agent and a severe mucous membrane irritant. It is a corrosive and if ingested can cause nausea, vomiting and kidney damage. It can react vigorously or explosively with many chemicals and will spontaneously combust with glycerol or ethane 1-2:diol. Check for compatibility before adding to other chemicals.
EYES - Code 2; SKIN - Code 5; INHALED - Code 15; INGESTED - Code 27

RESORCIN: is a quinone imine dye and a potential carcinogen. Its toxicity has not been quantified. Handle with care.
EYES - Code 3; SKIN - Code 12; INHALED - Code 16; INGESTED - Code 24

SILVER NITRATE: is a caustic substance and can cause burns. It is toxic if ingested, the silver being absorbed into the bloodstream followed by deposition in a variety of body tissues. It is a severe eye irritant. In contact with a combustible substance silver nitrate can cause fire. Silver nitrate splashed on to the skin will oxidise on contact to a black compound which is difficult to remove.
EYES - Code 2; SKIN - Code 5; INHALED - Code 14; INGESTED - Code 20

SODIUM HYDROXIDE: causes severe burns which heal slowly. A liquid splash to the eye can cause blindness. It will cause severe damage to all mucous membranes. It is toxic when ingested.
EYES - Code 3; SKIN - Code 5; INHALED - Code 16; INGESTED - Code 21

SODIUM IODATE: is an eye and respiratory tract irritant and is mildly toxic when ingested. Contact with a combustible material may cause fire.
EYES - Code 2; SKIN - Code 5; INHALED - Code 14; INGESTED - Code 21

SODIUM NITRITE: is a potential carcinogen and is highly toxic. It must never be handled during pregnancy. It is corrosive and burns to the eye can cause permanent damage. It is a strong irritant to the eyes, skin and respiratory tract and can act as a skin sensitiser. Handle with great care.
EYES - Code 3; SKIN - Code 6; INHALED - Code 15; INGESTED - Code 27

SODIUM THIOSULPHATE: is regarded as having a low toxicity. It is a mild irritant.
EYES - Code 2; SKIN - Code 5; INHALED - Code 14; INGESTED - Code 26

SULPHURIC ACID: is a corrosive substance and a strong irritant. It must be handled with care. It will cause severe burns to exposed skin and eyes and can cause severe respiratory and gastrointestinal disorders. The vapour is also a severe irritant and corrosive. Always add acid to water and never water to acid. Heat is generated by the reaction which can be violent.
EYES - Code 3; SKIN - Code 5; INHALED - Code 14; INGESTED - Code 20

URANYL NITRATE: is a radioactive substance and its effects are cumulative. It is highly toxic when inhaled or ingested. It is an eye irritant and can be absorbed through cuts and abrasions.
EYES - Code 3; SKIN - Code 6; INHALED - Code 16; INGESTED - Code 21

VICTORIA BLUE: is an aminotriarylmethane dye. Its effects upon humans have not been quantified. Other dyes in this group are known to be very toxic and potential carcinogens. Handle with care.
EYES - Code 3; SKIN - Code 12; INHALED - Code 16; INGESTED - Code 21

XYLENE: is a moderately flammable liquid which is a mild eye and mucous membrane irritant. It is a primary skin irritant and a central nervous system depressant. It will defat skin and may cause dermatitis. Death has been caused from over exposure due to respiratory failure.
EYES - Code 2; SKIN - Code 12; INHALED - Code 15; INGESTED - Code 27