Special Tissues - Safety Data

ABSOLUTE ETHANOL: is a flammable liquid and should never be handled close to heat or naked flame. The vapour is heavier than air and can travel for a considerable distance along the ground to a source of ignition and flash back. Ethanol is regarded as one of the safest industrial solvents because although it possesses narcotic properties, vapour concentrations sufficient to produce narcosis are rarely, if ever, reached in a medical laboratory. Ethanol is rapidly oxidised in the body to carbon dioxide and water and does not produce permanent damage to the central nervous system.
EYES - Code 1; SKIN - Code 4; INHALED - Code 14; INGESTED - Code 18

ACRIDINE ORANGE: The acridine group of dyes has been known to cause hypersensitivity reactions. Acridine orange is moderately toxic, an eye and respiratory tract irritant and a combustible powder that should not be handled close to heat or naked flame.
EYES - Code 2: SKIN - Code 12: INHALED - Code 15: INGESTED - Code 20

ACETIC ACID: is a corrosive substance and will cause severe damage to exposed skin. Ingestion will cause dental erosion, bronchitis and respiratory difficulties. It is an eye and mucous membrane irritant.
EYES - Code 3; SKIN - Code 5; INHALED - Code 14; INGESTED - Code 20

ACID FUCHSIN: is a triaminotriarylmethane dye. It is a skin, eye and mucous membrane irritant and is toxic if ingested. It can cause conjunctivitis and prolonged skin contact may cause dermatitis. Ingestion may cause nausea, vomiting and diarrhoea.
EYES - Code 3; SKIN - Code 12; INHALED - Code 16; INGESTED - Code 24

ALUMINIUM SULPHATE: is a skin and eye irritant and is mildly toxic when ingested. It is hygroscopic and prolonged skin contact may cause dermatitis. Acute exposure to skin and eyes causes redness and pain. Ingestion may cause abdominal pain, vomiting and diarrhoea.
EYES - Code 2; SKIN - Code 5; INHALED - Code 14; INGESTED - Code 21

AMMONIUM HYDROXIDE: has a moderate fire and explosion risk when exposed to a naked flame in a confined space. It is a severe irritant and is corrosive. The vapour is also a severe irritant and corrosive. A splash to the eye will cause severe burns. Skin contact will result in localised irritation and may cause burns. Inhalation of the vapour causes convulsive coughing. Prolonged exposure may lead to permanent lung damage. Ingestion will cause localised burns in the mouth, oesophagus and gastrointestinal system.
EYES - Code 3; SKIN - Code 5; INHALED - Code 16; INGESTED - Code 27

ANILINE BLUE: is a triaminotriarylmethane dye. It is a potential bladder carcinogen. It is very toxic and can be absorbed through the skin and respiratory tract. It can cause liver and kidney damage and anaemia.
EYES - Code 2; SKIN - Code 12; INHALED - Code 16; INGESTED - Code 24

CALCIUM CHLORIDE: is a skin, eye and respiratory tract irritant and is moderately toxic when ingested. It is hygroscopic and prolonged skin contact may cause dermatitis.
EYES - Code 2; SKIN - Code 5; INHALED - Code 14; INGESTED - Code 27

CELESTIN BLUE: is a quinone-imine dye. Its effects have not been quantified but other dyes in this group are potential carcinogens. Handle with care.
EYES - Code 2; SKIN - Code 12; INHALED - Code 16; INGESTED - Code 24

CELLOSOLVE (2-ethoxyethanol): is a flammable substance and should never be handled close to heat or naked flame. The vapour is heavier than air and can travel along the ground for a considerable distance to a source of ignition and flash back. It is an irritant and a neurotoxin. It is also a teratogen and should not be handled during pregnancy. This is a very dangerous substance and should be handled with the greatest of care.
EYES - Code 3; SKIN - Code 5; INHALED - Code 15; INGESTED - Code 21

CHROMOTROPE 2R: is a monoazo dye. The toxic effects upon humans have not been quantified but other dyes in this group are carcinogenic and very toxic. Handle with care.
EYES - Code 3; SKIN - Code 12; INHALED - Code 15; INGESTED - Code 21

N-DIMETHYL FORMAMIDE: is an embryotoxin and a potential carcinogen. It must never be handled during pregnancy. It is an eye, skin and respiratory tract irritant. Ingestion may cause irreversible liver damage.
EYES - Code 3; SKIN - Code 6; INHALED - Code 16; INGESTED - Code 29

DISODIUM HYDROGEN ORTHOPHOSPHATE: is a toxic substance and can be absorbed into the body by inhalation or ingestion. It is an eye and skin irritant. Inhalation or ingestion may cause sore throat, coughing and abdominal pain. Eye and skin contact may cause redness and pain.
EYES - Code 2; SKIN - Code 5; INHALED - Code 14; INGESTED - Code 21

DITHIOTHREITOL: Toxicity data for this compound are not yet available. Handle with care.
EYES - Code 2; SKIN - Code 12; INHALED - Code 15; INGESTED - Code 17

DULBECCO’S EAGLE’S TISSUE CULTURE MEDIUM: will cause irritation to the eyes and skin. Commercially manufactured preparations may not have been checked for virus and bacterial contamination.
EYES - Code 3; SKIN - Code 9; INHALED - Code 14; INGESTED - Code 22

FORMALDEHYDE: is a moderately flammable liquid when exposed to heat or a naked flame. It is an animal carcinogen, a strong eye, skin and mucous membrane irritant and skin sensitiser. Death has been reported in workers exposed to high levels of formalin vapour.
EYES - Code 3; SKIN - Code 12; INHALED - Code 16; INGESTED - Code 24

FORMIC ACID: is a strong corrosive and an irritant to skin, eyes and mucous membranes. The vapour is also an irritant and corrosive. Severe burns can result from exposure. Chronic bronchitis, painful breathing, nausea, vomiting, dental erosion and sensitisation can also occur.
EYES - Code 2; SKIN - Code 12; INHALED - Code 14; INGESTED - Code 21

GELATIN: is considered to be safe. It will cause eye irritation.
EYES - Code 2; SKIN - Code 11; INHALED - Code 14; INGESTED - Code 18

GIEMSA: is composed of a mixture of dyes which normally includes azure A, azure B and methylene blue. All are quinone-imine dyes in the thiazin sub group and all are very toxic and irritate eyes and skin. The powder is flammable and should never be handled close to heat or a naked flame.
EYES - Code 2; SKIN - Code 5; INHALED - Code 16; INGESTED - Code 28

GLYCEROL: is an eye irritant, otherwise it is regarded as being safe. It is hygroscopic and prolonged skin contact can cause dermatitis in sensitive individuals.
EYES - Code 2; SKIN - Code 11; INHALED - Code 14; INGESTED - Code 19

GOLD CHLORIDE: is an eye irritant and may irritate the skin of sensitive individuals. It is regarded as being of low toxicity.
EYES - Code 2; SKIN - Code 4; INHALED - Code 14; INGESTED - Code 19

HAEMATOXYLIN: is a natural dye and a flammable powder and should not be handled close to heat or naked flame. It is a mild irritant to eyes, skin and mucous membranes. Its toxicity has not been quantified. Handle with care.
EYES - Code 2; SKIN - Code 11; INHALED - Code 14; INGESTED - Code 19

HYDROCHLORIC ACID: is a strong irritant and corrosive and must be handled with great care. It will cause severe burns to exposed skin and eyes. The vapour is also a strong irritant and corrosive. Always use a fume hood when handling this acid. ALWAYS add acid to water and NEVER water to acid as heat is generated which can cause a violent reaction.
EYES - Code 3; SKIN - Code 9; INHALED - Code 14; INGESTED - Code 22

HYDROGEN PEROXIDE: is a strong oxidising agent and is very corrosive. It is a severe eye and mucous membrane irritant. Exposure of the eyes to the vapour causes irritation whilst a liquid splash causes severe burning with loss of sight. A liquid splash to the skin will burn and bleach but there should not be permanent damage. Inhalation of the vapour will irritate the mucous membranes with coughing and shortness of breath. Ingestion of the liquid will cause localised burning and severe irritation.
EYES - Code 3; SKIN - Code 5; INHALED - Code 15; INGESTED - Code 19

HYDROQUINONE: is a toxic substance which may cause dizziness, nausea, vomiting, headache, cyanosis, delirium and ultimatly collapse. Skin contact may cause dermatitis. It is an eye irritant.
EYES - Code 2; SKIN - Code 11; INHALED - Code 14; INGESTED - Code 20

IODINE: is a toxic and corrosive solid which attacks the central nervous system and the gastrointestinal tract. It can cause kidney damage and can be absorbed through the skin in doses large enough to cause toxicity. Inhalation can cause erosion of the respiratory tract. Over-exposure to iodine vapour can be fatal. This is a very dangerous substance and should be handled with extreme care.
EYES - Code 3; SKIN - Code 5; INHALED - Code 16; INGESTED - Code 31

ISOPROPANOL: is a flammable liquid and should never be handled close to heat or a naked flame. Vapours are heavier than air and can travel along the ground for a considerable distance, to a source of ignition and flash back. It is a severe eye, skin and mucous membrane irritant and a central nervous system depressant. Death may occur from respiratory paralysis.
EYES - Code 2; SKIN - Code 5; INHALED - Code 16; INGESTED - Code 24

LIGHT GREEN: is a diaminotriarylmethane dye which is a combustible powder and should never be handled close to heat or naked flame. It is a known carcinogen and should be handled with extreme care. Avoid skin contact and inhaling the powder. It is an eye and respiratory tract irritant.
EYES - Code 3; SKIN - Code 12; INHALED - Code 15; INGESTED - Code 20

MERCURIC CHLORIDE: is toxic and corrosive and may be absorbed into the body by inhalation, ingestion or through the skin. It can cause blurred vision, sore throat, metallic taste, coughing, shortness of breath and laboured breathing. Its toxic effects are cumulative and large doses which affect the kidneys and the central nervous system can be fatal.
EYES - Code 3; SKIN - Code 7; INHALED - Code 15; INGESTED - Code 27

METHANOL: is a flammable liquid and should never be handled close to heat or naked flame. The vapour is heavier than air and can travel for a considerable distance along the ground to a source of ignition and flash back. It has a mutagenic effect upon animals and should never be handled during pregnancy. The vapour and liquid are eye, skin and mucous membrane irritants and central nervous system depressants. They are narcotics and can cause death. The liquid defats skin and can cause dermatitis and can be absorbed through the skin in doses large enough to cause narcosis. Inhalation of 800 to 1000 ppm of vapour is sufficient to cause blindness. Exposure to 50,000 ppm for 1 to 2 hours will result in death.
EYES - Code 3; SKIN - Code 13; INHALED - Code 16; INGESTED - Code 28

MOUNTING MEDIUM: usually xylene or toluene based and the effects are as for xylene.
EYES - Code 2; SKIN - Code 12; INHALED - Code 15; INGESTED - Code 27

NAPHTHOL-AS-D CHLOROACETATE: is a potential carcinogen and should not be handled during pregnancy. It is an eye, skin and respiratory tract irritant and is moderately toxic.
EYES - Code 3; SKIN - Code 9; INHALED - Code 14; INGESTED - Code 20

NEUTRAL RED: is an azin dye. It is a combustible powder and should never be handled close to heat or naked flame. It is an eye and skin irritant and may cause dermatitis. It is a toxic substance.
EYES - Code 3; SKIN - Code 6; INHALED - Code 16; INGESTED - Code 21

NUCLEAR FAST RED: is a member of the anthraquinone group of dyes. Little is known about its toxicity so the dye powder should be handled with extreme care. Its chemical structure suggests that it will be an eye and respiratory tract irritant and may be toxic.
EYES - Code 3; SKIN - Code 12; INHALED - Code 14; INGESTED - Code 20

ORANGE G: is a monoazo dye. It is a mutagen and should never be handled during pregnancy. It is very toxic.
EYES - Code 3; SKIN - Code 13; INHALED - Code 16; INGESTED - Code 24

PARAFORMALDEHYDE: the dust is a strong eye, skin and mucous membrane irritant and skin sensitiser. Eye contact will cause burns to the cornea. It is highly toxic when inhaled or ingested.
EYES - Code 3; SKIN - Code 12; INHALED - Code 16; INGESTED - Code 24

PARAROSANILIN: is a triaminotriphenylmethane dye. It is a potential carcinogen and as such should be handled with care. Its toxicity has not been quantified.
EYES - Code 2; SKIN - Code 11; INHALED - Code 14; INGESTED - Code 19

PHOSPHOMOLYBDIC ACID: is a skin and eye irritant. It is toxic if inhaled or ingested. Molybdenum compounds are rapidly excreted from the body so that small doses rarely cause more than discomfort.
EYES - Code 2; SKIN - Code 12; INHALED - Code 16; INGESTED - Code 21

PHOSPHOTUNGSTIC ACID: is an eye irritant and is mildly corrosive. It is harmful to inhale the powder.
EYES - Code 2; SKIN - Code 12; INHALED - Code 15; INGESTED - Code 21

PHLOXINE: is a xanthene dye. It is highly toxic and an eye and skin irritant.
EYES - Code 3; SKIN - Code 12; INHALED - Code 16; INGESTED - Code 24

PICRIC ACID: is a strong oxidising agent which reacts violently with combustible materials and reducing agents. It is toxic and can be absorbed into the body by inhalation of the vapour or ingestion of the liquid. It is an eye, skin and respiratory tract irritant, a neurotoxin and can cause convulsions. The powder is explosive when dry and should therefore always be stored under water in a container with a cork stopper.
EYES - Code 2; SKIN - Code 6; INHALED - Code 16; INGESTED - Code 21

PINACYANOL: Toxicity data for this compound are not yet available. Handle with care.
EYES - Code 2; SKIN - Code 12; INHALED - Code 15; INGESTED - Code 17

POTASSIUM IODIDE: is highly corrosive and toxic. It is a severe eye and respiratory tract irritant and will cause burns to the skin. If ingested it will cause severe abdominal pain. Inhalation leads to irreversible lung damage.
EYES - Code 2; SKIN - Code 6; INHALED - Code 16; INGESTED - Code 31

POTASSIUM METABISULPHITE: is an irritant and is corrosive. In the presence of moisture it will liberate sulphurous acid which can cause severe burns to the eyes, respiratory tract and skin when the skin is moist. Ingestion will cause severe pain whilst large doses may cause colic and diarrhoea, circulatory disturbances and depression of the nervous system resulting in death.
EYES - Code 2; SKIN - Code 5; INHALED - Code 16; INGESTED - Code 21

POTASSIUM PERMANGANATE: is an oxidising agent and a severe mucous membrane irritant. It is corrosive and if ingested can cause nausea, vomiting and kidney damage. It can react vigorously or explosively with many chemicals and will spontaneously combust with glycerol or ethane 1-2:diol. Check for compatibility before adding to other chemicals.
EYES - Code 2; SKIN - Code 5; INHALED - Code 15; INGESTED - Code 27

RHODAMINE: is a xanthene dye. It is an eye and skin irritant and toxic by inhalation or ingestion. Overexposure may cause liver and thyroid damage. A fine mist of dust can create a dust explosion.
EYES - Code 2; SKIN - Code 5; INHALED - Code 15; INGESTED - Code 21

SILVER NITRATE: is a caustic substance and can cause burns. It is toxic if ingested, the silver being absorbed into the bloodstream and deposited in a variety of body tissues. It is a severe eye irritant. In contact with a combustible substance silver nitrate can cause fire. Silver nitrate splashed on to the skin will oxidise on contact to a black compound which is difficult to remove.
EYES - Code 2; SKIN - Code 5; INHALED - Code 14; INGESTED - Code 20

SODIUM ACETATE: is moderately toxic by ingestion and is an eye, skin and mucous membrane irritant. Acute exposure to the eyes may cause redness, pain and irritation. Inhalation may cause coughing, dyspnoea and respiratory distress. Ingestion may cause nausea, sore throat, coughing and abdominal pain.
EYES - Code 2; SKIN - Code 12; INHALED - Code 16; INGESTED - Code 31

SODIUM DIHYDROGEN ORTHOPHOSPHATE: is an eye and respiratory tract irritant. There is only slight toxicity if ingested, however, large amounts may cause metabolic disturbances.
EYES - Code 2; SKIN - Code 11; INHALED - Code 14; INGESTED - Code 20

SODIUM NITRITE: is a potential carcinogen and is highly toxic. It must never be handled during pregnancy. It is corrosive. Burns to the eye can cause permanent damage. It is a strong irritant to the eyes, skin and respiratory tract. It can act as a skin sensitiser. Handle with great care.
EYES - Code 3; SKIN - Code 6; INHALED - Code 15; INGESTED - Code 27

SODIUM SULPHITE: is an eye, skin and respiratory tract irritant and is a corrosive substance. When inhaled it can cause sore throat, coughing, shortness of breath and lung oedema. If ingested, abdominal pain, vomiting and diarrhoea may result with kidney damage.
EYES - Code 2; SKIN - Code 5; INHALED - Code 15; INGESTED - Code 21

SODIUM THIOCYANATE: This is a corrosive substance that will cause burns to eyes, skin and mucous membranes. It is a toxic substance that can be absorbed through the skin. Toxicity causes weakness, confusion, diarrhoea and skin rashes.
EYES - Code 3: SKIN - Code 6: INHALED - Code 15: INGESTED - Code 21

SODIUM THIOSULPHATE: is regarded as having a low toxicity. It is a mild irritant.
EYES - Code 2; SKIN - Code 5; INHALED - Code 14; INGESTED - Code 26

TARTRAZINE: is a monoazo dye. Its effects upon humans has not been quantified but other dyes in this group are very toxic and carcinogenic.
EYES - Code 3; SKIN - Code 12; INHALED - Code 16; INGESTED - Code 24

TOLUIDINE BLUE: is a quinone-imine dye which is a combustible powder and should never be handled close to heat or naked flame. It is an animal mutagen and should not be handled during pregnancy. The powder is an eye and respiratory tract irritant. Its toxicity in humans has not been quantified but it has proven to be highly toxic to laboratory animals.
EYES - Code 2; SKIN - Code 5; INHALED - Code 16; INGESTED - Code 17

XYLENE: is a moderately flammable liquid which is a mild eye and mucous membrane irritant. It is a primary skin irritant and a central nervous system depressant. It will defat skin and may cause dermatitis. Over exposure has led to death from respiratory failure.
EYES - Code 2; SKIN - Code 12; INHALED - Code 15; INGESTED - Code 27